​Graduate research, investigation of short-term sulforaphane intervention on NRF2 signaling and the gut microbiome in older adults. Previous studies from our laboratory have shown that as we age, our cells are less able to respond in terms of the ability to protect from stress and adaptation to exercise is attenuated, as compared to young. Research has shown that age-related gut microbiome composition, known as dysbiosis, have been linked to various health issues, including inflammation, impaired immune and cognitive function, and increased susceptibility to diseases. The purpose of this study is to test whether sulforaphane, a phytonutrient found naturally in certain cruciferous vegetables, can improve measures of cell defenses in the blood and restore gut health. The results will serve as preliminary data for a future study where we plan to pair the supplement with an exercise intervention to investigate whether the combination will further boost the response seen by an exercise intervention alone.